Harley Quinn with be making her film début in Suicide Squad soon and I think its fair to say people are most excited about her character above all overs. Margot Robbie who is playing Quinn has somewhat stolen the show.
So naturally it makes sense that she will be the lead in a new female lead DC movie. Characters that could share the screen with her could be, Batgirl, Birds of Prey, Poison Ivy (my fav), Katana and Bumblebee.
Will be interesting to see how this develop's I will be keeping an eye out for news, especially the casting of certain characters.
Robbie, whose appearance as Harley Quinn in trailers for David Ayer’s forthcoming Suicide Squad film has created enormous anticipation for the supervillain epic, presented the project to studio executives with an unnamed writer on board. The Australian actor plans to produce the movie and star as Quinn, who in the comics is best known as the Joker’s paramour and partner in crime. The Hollywood Reporter suggests characters such as Batgirl, Birds of Prey, Poison Ivy, Katana and Bumblebee could all be involved in the new film. DC, whose back catalogue is entirely owned by Warner for big-screen licensing purposes, has had huge success recently with a line of comics and related products aimed at its burgeoning female readership, DC SuperHero Girls.
http://www.theguardian.com/film/2016/may/17/margot-robbie-harley-quinn-female-dc-comics-book-movie